Where We Left Off: Season 6 ended on the mother of all cliffhangers as the Winchesters’ angelic ally Castiel absorbed all the souls of Purgatory and declared himself God, threatening to destroy the brothers if they didn’t bow down and worship him … say it ain’t so, Cas!

What's Next: At Comic-Con, it was revealed that Season 7 would see Sam and Dean on the run with many of their old tricks and hiding places rendered useless in the face of a new and unpredictable foe. Castiel’s megalomaniacal makeover will be addressed in the first couple of episodes, and the destruction of the mental wall holding back Sam’s memories of hell will be an ongoing concern throughout the year.

Season 7 premieres Fri., Sept. 23, 9PM ET on The CW