Having a terrific brother myself, I have a great affection for brother-sister teams. Together, they work past the boring notion of sibling rivalry to achieve greatness. Amy and David Sedaris on the New York Theater Workshop stage. Jake and Maggie Gyllenhaal in Donnie Darko. John and Joan Cusack in just about every film either one of them has made. Now, another team is looking to make the list of great brother-sister working relationships. David Arquette will be directing big sis Patricia in an upcoming episode of Medium.

Patricia had this to say about the collaboration: "I was always a bossy little girl and being David's older sister I've bossed him around quite a bit. Now that he'll be directing me it will be payback time...I feel so safe with him. I think I'll be able to go to some of my darkest places." That's kinda creepy, but whatever, you work out those family neuroses. When you're done, maybe you could straighten those Baldwins out.