The X-Files was a one-of-a-kind, groundbreaking show. It took the typical FBI detective show and spun it, but good. Add some aliens and government conspiracy and you've done one better than a weekly FBI caper.

And the extraterrestrial and supernatural make for some good quotes, starting with the pilot, when Scully refers to Mulder by his nickname from the academy: "Spooky Mulder."

Or how about Mulder's understatement of the millennium: " ... in most of my work, the laws of physics rarely seems to apply."