After losing co-founder Joseph Barbera and animator Ed Benedict, Hanna Barbera is again saying good-bye to yet another legend. Iwao Takamoto, who designed Scooby-Doo, Shaggy and the rest of the Mysteries Inc. gang, passed away yesterday at the age of 81.

While Ed Benedict is credited with designing the original Flintstones characters, Takamoto designed the Great Gazoo. He also created Muttley, the wheezing dog featured on such shows as Laff-A-Lympics, Dastardly & Muttley in Their Flying Machines and Wacky Races; and Astro, the Jetson's dog who, oddly enough, sounded not unlike Scooby-Doo (both were voiced by Don Messick). His other credits at Hanna Barbera include Josie and the Pussycats, Jabberjaw and many, many others.