Cinemax has announced that production is underway on 'Nemesis,' its new drama series set in the world of international espionage. Created and written by Frank Spotnitz ('The X Files,' 'Strike Back'), 'Nemesis' stars Melissa George ('In Treatment,' 'Home and Away'), Adam Rayner ('HawthoRNe'), Stephen Dillane ('Game of Thrones'), Morven Christie ('The Young Victoria') and Adewale Akinnuoye-Agbaje ('Lost').

The eight-part series is is produced by Kudos Film & Television ('MI-5,' 'Life on Mars') for BBC One and HBO/Cinemax in association with Big Light Productions. It will shoot in Scotland, London and Morocco, and is slated to air on Cinemax in 2012.

Spotnitz will executive-produce along with Alison Jackson, Jane Featherstone and Stephen Garrett from Kudos Film & Television and Christopher Aird from the BBC. Eliza Mellor ('Albert Schweitzer,' 'Derek') produces, and SJ Clarkson ('Heroes,' 'Life On Mars') will direct the first two episodes.

Odette Annable is joining the cast of 'House' as a series regular. Fear not, 'Breaking In' fans, there is a plan in place should Fox decide to revive the Christian Slater comedy.

According to Deadline, Annable's deal with the show does allow her time to go back to 'Breaking In' if the show gets a Season 2 from Fox.

No details on Annable's new 'House' character have been released, other than that she meets House in prison.

Producers are still looking to cast a replacement for Lisa Edelstein's boss character.

In other casting news ...

'Lie to Me' is putting together one of the best casts of recur and guest stars of any two-season-old TV show.

Veteran TV and movie actor Melissa George will star on Fox's 'Lie to Me' as a recurring character later this season, Entertainment Weekly reports. She comes off turns on 'Grey's Anatomy' and 'In Treatment,' the latter for which she received a 2008 Golden Globe nomination.

George will play an "Anna Nicole Smith-type" character named Clara Martin, the widow of a murdered billionaire that takes over her husband's business empire.

I've been a fan of Melissa George since I first saw her in 2001's short-lived Thieves. I was, quite possibly, the only person in the known universe who actually loved that show. She starred with John Stamos as lovers and professional thieves who worked a deal with the FBI. I guess I have a soft spot for anything that even resembles the 1960s show T.H.E. Cat, though there will never be anyone like Robert Loggia.

Melissa George has held assorted roles since then, including Lauren Reed in Alias, Laura in In Treatment, and Dr. Sadie Harris in Grey's Anatomy. These were great, but I don't think she's really found her place in TV history yet. But maybe that will change soon, because she's just nabbed the female lead in the CBS drama pilot US Attorney.

(S05E12) "You're wearing an alarmingly high pony tail." - Derek

At the most simplified level, Dunn is right, you know - a doctor isn't really that different than a serial killer. They both get to choose who dies. A doctor is likely driven by science while a serial killer gets his marching orders from a little voice in his head, but they're both making choices; doing what they think is the right move. Eric Stoltz has thus far been a shining point this season. William Dunn is one of the better characters we've seen on Grey's Anatomy in a while and I'm glad he'll be around for at least one more week.

Because I'm writing the Spoilers Anonymous column every week, I'm pretty much up-to-date with what is going to happen in our favorite TV series. However, I never saw the latest news from Entertainment Weekly's Michael Ausiello coming. Reading comments left in response to Ausiello's announcement and a post on the same subject written by E!'s Kristin Dos Santos, it looks like I'm not the only one extremely surprised by the news.

Usually, we get a few weeks warning before a major character leaves a series. But this time, we get about four days to prepare. As reported by Ausiello and many other entertainment media today, actress Brooke Smith is leaving the ABC hit series this Thursday. To learn more about her departure and what other tweaks the network asked the show to make, continue reading.

Spoilers ahead!

Grey's Anatomy is adding another bi-curious female doctor into the Hahn-Torres fray -- and it looks like she'll be played Melissa George. EW's Michael Ausiello reports that George, best known for her role as butt-kicking bad girl on Alias, is in final negotiations to play "an intern with, um, an open mind toward sexuality."

She's being positioned as a possible love interest for one of Seattle Grace's other two female-loving females, Callie Torres (Sara Ramirez) or Erica Hahn (Brooke Smith), who first locked lips in last year's season finale.

No word on exactly how long she'll stick around, but EW's sources suggest it'll be a while.

(S01E01) "I'm not dangerous, at least not to you." - Laura

After watching the premiere of In Treatment, I am only sure of one thing. I do not have the patience to be a therapist.

I was really distracted during the first half of the show because I couldn't figure out why none of my nerd friends told me that Eliza Dushku was on this show. That confusion eventually subsided when I realized that it was Melissa George with brown hair. I guess when you're a cat burglar or a spy you have to be blonde, but when you're troubled young waif, it's best to be brunette.

HBO continues to prepare for a post Sopranos world. There has been a lot of talk about their upcoming shows lately, including adapting George R. R. Martin's Song of Ice and Fire, David Milch's John From Cincinnati, and the untitled Kanye West project. We can now add two more to that list.

The network has picked up a one-hour comedy from producer Linda Bloodworth-Thomason (Designing Women) called 12 Miles Of Bad Road. The show will star Lily Tomlin as the matriarch of a rich Texas family. Add in the family real estate business and a collection of relatives and hilarity will ensue, hopefully. The idea almost sounds like a Dallas spoof. With Tomlin on board, it will certainly be worth a look. Look for Gary Cole, Mary Kay Place, and Leslie Jordan to also appear.