Talk about a poisoned cake! The same day NBC announces Las Vegas is renewed for a fifth season, series regulars James Caan and Nikki Cox announce they will not be part of the 2007-08 season.

TV Guide reports that Caan wants to focus on his movie career claiming that, even though he had a good time on the show, being part of Las Vegas made him miss a few good movie opportunities. Nikki Cox has yet to comment on her departure from the show.

The show can survive Cox leaving, even though it will crush the Danny/Mary shippers. But can it survive Caan's departure? His character is a pivotal one in the show and brings a unique flavor.

The season 4 finale, which will more than likely be Caan's and Cox's last episode unless the show convinces them to guest star, will air on March 9 at 9 p.m. EST on NBC.