Is Neil Patrick Harris now the hardest-working man in show business? These days he's juggling his duties on 'How I Met Your Mother' with a movie career that includes the much-buzzed-about 'Smurfs,' a hosting job with Sunday's '2011 Tony Awards and um, he's got 8-month-old twins.

But don't worry about NPH: He told Popeater little Gideon and Harper (with partner David Burtka) sleep 11 hours a night. We talked with the universally loved 'Doogie Howser' alum about what to expect during the show ("There will be the inevitable 'Spider-Man' jokes"), why he chose to raise his kids in the big city and he reveals details about the 'Smurfs' flick and how playing a coked-up hooker-lover changed his life forever.