You know that lady on 'Party Down' with short hair and pink glasses that just seems to earnest for her own good? That's Megan Mullally as Lydia, a Midwestern mom who moves to Hollywood to pursue her daughter's dreams of stardom and she's the latest edition to the band of misfits on 'Party Down' (Fri., 10PM ET on Starz).

Mullally's seasoned comedic chops are nourished by her co-stars Adam Scott, Ryan Hansen, Martin Starr and Ken Marino, whose behind-the-scenes pranks of leaving little gifts behind in trailer toilets feed into the insanity of the show.

The actress who may be best known as the bodacious Karen Walker on 'Will & Grace,' chatted with TV Squad to talk about her new role on one of the most critically-acclaimed, ratings-challenged shows, 'Karen: The Musical,' Children's Hospital' and a sing-off with 'Party Down' alumna Jane Lynch.

What is your role on 'Party Down'?
It's my new favorite show. I'm playing a dorky screwball caterer Lydia in the company called Party Down. [She] is this clueless, bright eyed and bushy tailed woman from the Midwest who comes to Hollywood with her 12 year-old daughter Escapade who is going to be a star. This season we're catering backstage at a def-metal concert and we're catering an orgy. I have a crush on every person in that show including Lizzy Caplan. I would literally make out with any of those people although that would be kind of disgusting because three of them are in their 20s and I'm 51!

Yes, Jane Lynch has gone off to more 'Glee'-ful pastures, but thanks to new star Megan Mullally, the second season of Starz' buzzworthy comedy 'Party Down' (premieres April 23, 10PM ET), isn't missing a single drop of the funny.

Mullally, the two-time 'Will & Grace' Emmy winner, joins the Party Down catering crew -- as Lydia Dunfree, a recently-divorced mom who has moved to Los Angeles so her daughter, Escapade, can become the next big kid star. Yes, that's right, Escapade ... sounds like something Mullally's Karen Walker would name her kid.

And speaking of the scene-stealing 'Will & Grace' character, Mullally will also soon bring her iconic TV alter ego to theater stages. 'Karen: The Musical' is currently in development, and Mullally talked to AOL TV about Karen's return to pop culture (and the Karen spin-off series that could have been), her 'Party' days, her gig as the I Can't Believe It's Not Butter spokeswoman, guest-starring with hilarious hubby Nick Offerman on 'Parks and Recreation' and which 'Saturday Night Live' star she helped discover.

Drugs on TV have had a strange history. There have been after-school movies, very special sitcom episodes and even entire dramas based around illegal substances.

Sometimes, drug abuse on TV is used to teach the audience a lesson, while other times writers have characters develop an addiction as a way of making them more human in a flawed sense.

One of the most recent drug abusers comes to us in the form of Edie Falco's title character on 'Nurse Jackie.' The medical drama is back with a vengeance (Mon., March 22 10PM on Showtime), and to celebrate the return of our favorite no-nonsense RN, we're taking a look at TV's other famous pill-popping characters we've come to love (despite their issues) over the years.

We're not endorsing drug abuse of any kind, but it's a fact of life for some people, including these TV characters.

Find out who made our list after the jump.

The new shows keep rolling off the assembly line, including this one starring actor Patrick Fugit.

The actor has been picked up for a new sitcom pilot from ABC called 'Wright vs. Wrong' along side 'Will & Grace' actress Debra Messing.

Messing plays a conservative pundit juggling her "public persona despite facing her own vulnerabilities." Fugit plays a writer to the pundit, described as a "liberal NYU graduate." Think of it as an 'Odd Couple' but with more accusations of being a closet communist.

Grace is ready to try again. Actress Debra Messing has signed for a new television show called 'Wright vs. Wrong,' a sitcom for ABC, and if you think this is going to be anything like 'Will & Grace,' think again. (Although if they're smart, it better be just as funny!)

The premise of the pilot for 'Wright vs. Wrong' is that Debra plays Evelyn Wright, a strong-minded, ambitious political personality who espouses the conservative, right-wing agenda. However, while she has this tough, conservative personality for the public, behind the scenes she's consumed by her foibles and flaws.

So she's half-Grace Adler, the flawed, foibled part. Grace's politics, at least what she tried to articulate in her goofy way, was of the liberal lefty variety.

Have you seen Will and Grace star Megan Mullally in her latest production? No, not her work in the theater, including an upcoming revival of Lips Together, Teeth Apart. I'm talking about her butter commercial. Yes, yes, that's Megan Mullally in the "Turn the Tub Around" I Can't Believe It's Not Butter commercials.

I have to admit, when I first saw the commercial, I was stunned. It was the strangest margarine ad since William Shatner's classic Promise spots. But the more I've seen of Megan's disco-inspired musical extravaganza for I Can't Believe It's Not Butter, the more I think that the whole thing is hilarious. Megan, in my estimation, has her tongue firmly in cheek.

More of our best of the decade coverage, which started on Tuesday. You can read the other posts at the link above. Here, we talk about the women who made us laugh the most during the decade.

Since Lucille Ball, television has been a bastion of funny ladies, and the '00s were no exception. Like Lucy, many of the women on this list played second fiddle to no one. And those that weren't the stars of their own shows managed to steal the scene anyway the moment they got in front of the camera.

The '00s will probably go down in television history as one of those decades where the sitcom sputtered and almost died -- again! But it's alive and well now, with an amazing turn-around in 2009. But, as this list proves, it was never truly in danger. Throughout the decade these women provided plenty of laughs in both the hour and half-hour formats, proving that as long as we want to laugh, there will be brilliant actresses around to crack us up.

Here's our list of the top funny ladies of the decade:

Recently, we were inspired by 'Parks and Recreation' to write a feature listing TV shows that overcame a rocky launch. Sadly, the reverse seems more common: shows that start strong but finish weak.

Our latest inspiration is the ongoing death spiral of 'Heroes.' (This week: Mohinder does something stupid! People's powers go awry at inopportune moments! Adrian Pasdar, pictured, looks like he'd rather be anywhere else!) Here's a once-inspired show that seems to be going down in flames after having run out of ideas.

Other times, shows peter out because of casting changes, bad writing or bizarre creative decisions. In each case, however, the audience feels betrayed and often deserts the show, leading to ratings death and what-went-wrong autopsies. Here's what went wrong on nine other good shows gone bad.

For Justin Halpern, a guy who just a few months ago was unemployed and living with his 73-year-old father, Twitter has been a gold mine.

After selling a book based on his popular Twitter feed, 'Sh*t My Dad Says,' to Harper Collins last month, CBS is now getting into the 'Dad' game by developing it into a series, according to the Hollywood Reporter.

On his Twitter account, Halpern simply posts choice quotes that he heard around the house while he was still unemployed. Immediately, the feed boasted hundreds of thousands of followers, thanks to nuggets like "Son, no one gives a sh*t about all the things your cell phone does. You didn't invent it, you just bought it. Anybody can do that" and "You worry too much. Eat some bacon... What? No, I got no idea if it'll make you feel better, I just made too much bacon."

If I didn't love this news so much, I'd be worried that 30 Rock was turning into The Love Boat or Will and Grace. After all, it seems as though there's news of a new guest star every few days. First Will Arnett signed on to reprise his role as the delightfully evil Devon Banks, then ex-Friend, Jennifer Aniston, decided to return to television in order to stalk Jack Donaghy. After that came news that Oprah was scheduled to play herself on an upcoming episode.

That's a lot of guest stars to pack into one season, but now we have news of two more. Everybody's favorite Gossip Girls, Blair and Serena, AKA Leighton Meester and Blake Lively, are coming to 30 Rock. What on earth could bring these Upper East Siders to Midtown? Are they trying to overthrow Liz Lemon as queen bee of TGS with Tracy Jordan? Are they starring in a movie with Tracy Jordan? There's more info on their storyline after the jump.

Debra Messing's Emmy-award winning miniseries The Starter Wife is getting some new cast members. Joining the former Will and Grace star are David Alan Bashe of Lipstick Jungle, Danielle Nicolet of Heartland, Brielle Barbusca of Hope & Faith, and Hart Bochner of Die Hard.

The USA original series follows the post-divorce hi-jinx of Molly Kagan (Messing) as she embarks on a new chapter in her life. USA is bringing back the hit miniseries for ten episodes this fall. Messing is now executive producer as well.

Bashe will play Molly's ex-husband, Kenny Kagen. Nicolet will play Liz Marsh, Molly's new friend and wife a a pro-baseball player. Barbusca will play Jaden, Molly and Kenny's daughter. And Bochner will play Molly's new love interest and writing class teacher. Returning for guest appearances is Joe Mantegna of Criminal Minds who plays Molly's former boyfriend Lou Manahan.

The series will premiere on USA in October. What do you think? Will The Starter Wife work as a full-fledged series?

When I interviewed Susanne Daniels, the President for Entertainment at the Lifetime Network, she was high on the success of Army Wives, and anxious to bring more comedy to the network.

"Viewers tell us that they love our comedies, our movies, Army Wives. I would argue that more people identify Reba and Will and Grace with our network now than the networks that launched them. And I was at the WB when Reba launched!" she said in TV Week. Well, now she's launching a new comedy, this time for Lifetime.

Lifetime has ordered 13 episodes of a new sitcom called Rita Rocks for this fall and cast Nicole Sullivan as Rita. The show will be part of a one-hour comedy block with Reba. "We've assembled a fantastic team in front of and behind the camera," said Ms. Daniels in a statement today.

Funny lady Megan Mullally may be coming back to the small screen! The actress, better known for her role of neurotic Karen Walker on NBC's Will & Grace, will star as the mother in ABC's new series Bad Mother's Handbook.

This comedy is about a 32-year-old woman (portrayed by Alicia Silverstone) who takes care of her 16-year-old daughter (played by Arrested Development's Alia Shawkat) and her 48-year-old overbearing mother (Mullally).

A roundup of TV people from in front of the camera and behind the scenes who have passed away.

• Jack B. Sowards: He was a television and film writer who wrote for Bonanza, Peyton Place, Daniel Boone, The Streets of San Francisco, Barnaby Jones, Hagen, The Bold Ones, B.L. Stryker, and Star Trek: TNG. He also wrote the big screen movie Star Trek II: The Wrath of Khan. He died in Valley Village, CA at age 78.