Sometimes you have to ask: Is a pet a hopeless case, or has he just not found the right home? That's the question on the latest 'Dog Whisperer' (Fri., 8PM ET on Nat Geo). Trainer Casar Millan is often the last hope for frustrated dog-owners. But in this case, the dog in question doesn't even have an owner.

You might call Maury "frisky," Or you might just call him "high-strung." Or you might even call him "insanely annoying." Maury has been in and out of the local animal rescue clinic. The big brown dog just has too much energy, and he inevitably ends up biting his new owner, then winding up in the shelter again. This has been going on for two years, and the staff at rescue services are starting to think he's unadoptable. Can Maury find a home in the world?

On 'Dog Whisperer' (Fri., 8PM ET on NAT GEO), Cesar Millan advises a husband and wife to "practice calmness with each other." He says, "It's how you deliver the message" -- both human to human and human to dog.

The woman thinks "that's a great thing. I mean, I would love to do that ... [Millan] not only does dog whispering, he does family counseling."

She goes on to tell Millan about problems at the dog park. When she gets worked up, she suddenly remembers to take a breath and be calm. "I'm already learning," the wife says.

On 'Dog Whisperer' (Fri., 8PM ET on NAT GEO), NASA astronaut Leland Melvin needs Cesar Millan's help with his two dogs.

Both Melvin and his canine Jake are anxious. Millan tells the owner, "It's more important that you pay attention [to] your energy ... They'd rather have a calm human than a human who's saying 'good boy.'"

As Melvin attempts to put a temporary muzzle on Jake, the dog gets agitated and bears his teeth. Millan notes that it's a nervous reaction, not aggression. Once Melvin takes control of the situation, everyone calms down.

Words can have double meanings. But the "Tsst!" sound is universal. It's an important lesson to learn. And on the new 'Daily Show' (weeknights, 11PM ET on Comedy Central), reporter Olivia Munn received some instruction from Cesar Millan, the "Dog Whisperer."

The Comedy Central correspondent had been reporting on a story involving cruelty to animals. In keeping with the show's satirical bent, Munn attacked a woman who opposed puppy mills in front of Mr. Millan -- one of the world's most famous dog-lovers.

Olivia complained to Cesar that she was having trouble with a "b*tch" -- which of course can also refer to a female dog. The camera then panned to the confused-looking Madeline Bernstein. Poor Ms. Bernstein was only trying to outlaw puppy mills -- commercial dog-breeding facilities that are notoriously overcrowded and inhumane.

Rhona Mitra is an English-born actress, model and singer. Naturally, her career requires her to travel all over the world. And Rhona acquired Oscar, her seven-year-old French bulldog, specifically because the breed was supposed to be good with traveling. But after a trip to South Africa, things started to go bad.

In South Africa, a pit bull attacked Oscar on the beach; the rival animal pinned him down and drew blood. Now, Oscar is nervous around other dogs -- but this caution expresses itself in the form of violence.

Mitra is afraid that Oscar will escape from her yard and start a fight in her "pit bull central" neighborhood of Venice, California. So on 'Dog Whisperer' (Sun., 7PM ET on Nat Geo), the actress turns to Cesar Millan for help.

Casey Anderson is the star of National Geographic's 'Expedition Wild' -- a show where he co-stars with an 800-pound grizzly bear. So you'd think he'd be used to dealing with wild beasts. But on the latest 'Dog Whisperer' (Fri., 8PM ET on Nat Geo), Casey has to deal with an entirely different type of animal -- his own two pet dogs.

Anderson and his wife -- actress Missi Pyle -- are having trouble with their two dogs: Dalmatian J.J. and Rottweiler mix Eleanor. If the canines are kept apart, then things are okay. But of course, J.J. and Ellie are always together -- and are always getting each other riled up. Casey can't handle it, so "dog whisperer" Cesar Millan comes in to help.

Cesar Millan is known as "the dog whisperer." But often, his technique focuses on reforming human behavior, rather than on the dogs themselves. On the new episode of 'Dog Whisperer' (Fri., 8PM ET on Nat Geo), Cesar meets Jaime Crossman and her dog Chloe, a Collie/Greyhound mixed-breed.

Jaime was warned of Chloe's behavior when she first got her pet. Chloe is extremely aggressive and attacks other dogs on sight. If she can't reach the other dog she takes out her frustration on her owner -- biting and nipping at Jaime's legs.

And speaking of "frustration," another animal trainer gave up on Chloe in despair. He called her a "genetic disaster" and recommended that she be put down. So the stakes are high. If Cesar can't reform Chloe, then she may be facing death.

Little Lola is scaring Howie Mandel. The tiny canine loves his wife but attacks everyone else. "I'm afraid for my life. It sounds like I'm kidding, but ... you don't want to come home and think that blood could be drawn," he tells Cesar Millan on 'Dog Whisperer' (Fri., 8PM ET on NAT GEO).

Mandel explains to the dog-rehab specialist that he can't touch his pet, due to having OCD. Millan replies, "You can't touch physically, but you can always touch energy-wise. You know, I always say, 'No touch, no talk, no eye contact.'"

"We've been married for 30 years, and those are the three things that've gotten us through," jokes Mandel.

The next time I have a panic attack, I want Cesar Millan to talk me off the ledge. He might be known as the Dog Whisperer on the National Geographic Channel, but I have a feeling he's great with humans, too. I'm sure I'd respond to his gentle "ch ch" murmurs just as well as the angry pit bulls he deals with regularly on Dog Whisperer with Cesar Millan.

The show celebrates its 100th episode on Sept. 19, and this household is officially hooked. There's something strangely meditative about the way he calms the dogs on that show. And, truthfully, it's not so much the dogs he works with as their nimrod human companions. Let's face it. The dogs are alright. The humans need work.

It's all about relationships, and his job, he says, is to draw out the good behavior in any given dog ("There are no killer dogs!"), and then tell the humans how to maintain it.