Giuliana Rancic somberly announced Monday on 'Today' that she would be getting a double-mastectomy in her fight against breast cancer. Rancic and her husband Bill stopped by 'The Wendy Williams Show' (weekdays, syndicated on ABC) on Tuesday, and tried to look at the bright side of her scary health situation. Rancic talked about the disease and her path forward, and had a few laughs about her treatment and Kim Kardashian's wedding.

As part of Rancic's double mastectomy, which will dramatically reduce the chance of the cancer's recurrence, she'll also be undergoing a breast reconstruction. "I'm doing reconstruction at the same time, so they might come out looking even hotter ... Bill helped pick them out and everything. I'm like, 'Bill, that big, really?' He always said he wasn't a boob man, but that's not true," she joked.

When it was revealed to the media recently that actress Christina Applegate had cancer, it was a shock. She is only 36 years old, but as anyone whose life has been touched by cancer, this disease touches the young and the old and everyone in between.

Today, the star of ABC's Samantha Who? was on Good Morning, America to explain what's happening with her, and Christina declared that she is now cancer-free. "Absolutely 100 percent clear and clean. It did not spread. They got everything out, so I'm definitely not going to die from breast cancer."

In an exclusive, candid interview, she revealed that three weeks ago she had a double mastectomy to remove all traces of breast cancer. She will have reconstructive surgery over the next eight months to replace her breasts.

I really admire Christina Applegate. I've liked her a lot on Samantha Who?, but to do what she did today makes me like her even more. She didn't have to face the media and talk about her cancer. It takes courage to share your story.

And having a positive diagnosis, to be able to say you're cancer-free, doesn't make it any easier to talk about the fear you face when you were told that you have cancer and must undergo a difficult surgery or chemotherapy or radiation.