(S11E06)

Mrs. Garrison: Kids, I need to tell you something that you might find a little shocking: I'm gay.

Stan: Again?

Longtime fans of South Park know that Mr./Ms. Garrison is a mercurial sexual beast. S/he's now been both straight and gay as a man and as a woman, but the one constant that remains is that whatever her preference happens to be that week, she takes it very seriously.

(S10E13)

Atheist in the future: Dawkins knew that logic and reason were the way of the future, but it wasn't until he met his beautiful wife that he learned using logic and reason isn't enough. You have to be a dick to everyone who doesn't think like you.

First of all, I don't watch a ton of science fiction, so who can tell me what the opening sequence was spoofing? It looked vaguely familiar, but my sci-fi exposure is rather limited. Help a brotha out, won't you?