Kat Von D announced via Twitter that she and Jesse James were splitting up, and then said that out of respect for their families she would say no more and thanked us for respecting that.

Chelsea Handler said no thank you to respecting anything and threw it up for discussion on the 'Chelsea Lately' (Weeknights, 11PM ET on E!) roundtable.

Jeff Wild determined that Von D must hate her father based on the men she's dating, while Jo Koy imagined how dimwitted and yet very civil their breakup must have been. But it was Natasha Leggero who provided the most intriguing insight.

"They're an interesting couple because they're both two hangers-on," she said. "There's no celebrity to anchor that relationship."

It doesn't really matter if you think Chelsea Handler's talk show is funny or not, because the TV casting gods have decided that it is.

Five -- count 'em five -- 'Chelsea Lately' comedians have secured lead and supporting roles on network TV shows this fall, and that's not counting how many guest spots the rest of them are probably lining up. So has the 'Chelsea Lately' roundtable become the new casting couch?

Now we should note that these aren't the first lucky/intrepid stand-ups to try to hit it big without Handler: Jen Kirkman famously quit her gig at 'Chelsea' to write for 'Perfect Couples' on NBC, but came back when that show got canceled. And roundtable regular Josh Wolf appeared on several episodes of 'Raising Hope' last season, but never really quit his "day job."

But a few full-time gigs might take the following funny people from late night to primetime for good ... or at least for a while. Take a look at what Chelsea's merry crew of inappropriate comedians will be up to next season.

Another week of TV has flown by and funny moments were plentiful. Witness a clumsy rescue that goes horribly awry, an embarrassed talk show host deny rumors that she's dating a rapper, a skit that skewers a tween idol, and a snarky robot who storms a red carpet event.

Chelsea Handler was blushing tonight. It's rare to see the sassy host look embarrassed -- usually, she's the one who's mocking other people. What could unnerve Ms. Handler? Well, a discussion of her rumored relationship with rapper 50 Cent did the trick. And it was Chelsea's own guest who turned against her.

Last week, Chelsea and 50 Cent were seen getting "hot and heavy" in a New Orleans bar. Handler has since denied that she is dating 50 Cent -- but the rest of the world basically assumes that they are getting it on. Tonight on 'Chelsea Lately' (Tue., 11PM ET on E!), guest Jo Koy couldn't take it anymore -- and confronted her with the accusations. Chelsea had some trouble denying the rumors this time around.

Please, Whitney Cummings. Please put your pants back on. The comedian pulls down her jeans to show off her underwear on 'Chelsea Lately' (weeknights, 11PM ET on E!), revealing what suspiciously looks like a large stain.

Sometimes, trouble just runs in the family. The new 'Chelsea Lately' (weeknights, 11PM ET on E!) takes on the important topic of an entire family that was arrested for drunk driving, all on the same night! First, the son was stopped at a police checkpoint for being drunk and stoned. The mom drove to the police station to rescue him ... but she showed up drunk! That's not good.

The mother was arrested, but that wasn't the end of the trouble for the family. Two hours later, her 45-year-old husband drove through the same police checkpoint, and was also arrested -- because he was also operating a vehicle while intoxicated. Yikes! Well, at least the mom, dad, and kid have a lot to bond over now.

We ran into some controversy on multiple fronts during 'Chelsea Lately' (weeknights, 11PM ET on E!). First, there were some lies and deception. Then, there was a discussion of Chelsea's potentially disgusting "club feet." Oh man. Things are getting a little out of hand here.

Comedian Jo Koy was one of the guests, and he was promoting his latest comedy show. But out of vanity, silliness, or just plain weirdness, Jo pretended that his show was sold out. Then it turned out that his show wasn't sold out. Chelsea Handler was mildly peeved by this. "YOU ARE SUCH A LIAR," she said to Jo. "YOU LIE ... ALL THE TIME."

Things get a bit personal between Chelsea Handler and comedian Jo Koy when talk turns to strippers, lap dances and the possibility that Handler has dental veneers on 'Chelsea Lately' (weeknights, 11PM ET on E!).

Chelsea Handler recruits a steady team of comedians for her Round Table topics on 'Chelsea Lately' (weeknights, 11PM ET on E!). She likes to treat them well, keep them happy.

For one such staffer, Jo "Josep!" Koy, Handler had a birthday surprise.

"On a serious note, it is your birthday," she said. "We want to do something nice for you. You're such a good sport about it, and all the gay jokes and all that stuff ... I wanted to get you something you can take home with you and enjoy away from us making fun of you."

Check out the video to find out what she got him.