• At 8, NBC has a new America's Toughest Jobs.
• TBS has the Red Sox/Rays game at 8.
• CNN has the new special Fall of the Fat Cats at 8.
• TLC has two new episodes of Flip That House at 8.
• Nickelodeon has a new iCarly at 8, followed by a new Naked Brothers Band.
• Also at 8: Food Network has a new Halloween episode of Unwrapped.
• At 9, CNBC has a new Suze Orman Show.
• BBC America has a new Primeval at 9.
• Lifetime has the movie Living Proof at 9.
• Cartoon Network has the movie Justice League: The New Frontier at 9.
• Sci-Fi has the movie Fire & Ice at 9.
• At 10, CBS has a new 48 Hours Mystery.
• TLC has a new Trading Spaces at 10
• At 11:30, SNL has a new Saturday Night Live, with Josh Brolin, Adele, and Sarah Palin.

Check your local TV listings for more.

Emmy and Grammy award winner Harry Connick, Jr. will star in the Lifetime original movie called Living Proof. The movie, currently being filmed in Connick's hometown of New Orleans, is produced by Renee Zellweger, Craig Zadan and Neil Meron who all worked on Chicago together. The film is about Dr. Dennis Slamon, the UCLA doctor who developed a drug for breast cancer. Living Proof tells the true story of this doctor's struggle to keep the drug trials going and save the lives of thousands of women.

Harry Connick, Jr. is joined by Amanda Bynes (Hairspray), Angie Harmon (Women's Murder Club), Swoosie Kurtz (Pushing Daisies), Bernadette Peters (Boston Legal), Jennifer Coolidge (American Pie), Regina King (Ray), Tammy Blanchard (Life with Judy Garland: Me and my Shadows), John Benjamin Hickey (Flags of Our Fathers), Paula Cale (Providence) and Trudie Styler (Empire).

The film will air in October as Lifetime's centerpiece for the network's annual awareness campaign Stop Breast Cancer for Life.

Academy Award and Golden Globe-winning actress Renee Zellweger is taking on another prestigious role: executive producer of a Lifetime Original Movie. Zellweger will produce Living Proof, based on the true story of Dr. Denny Slamon. Harry Connick, Jr. is playing Slamon, a doctor and developer of Herceptin 2, a type of breast cancer medication. According to E!, the actress has a personal connection to the Living Proof story. Nanci Ryder, Zellweger's publicist and friend, was one of Dr. Slaman's patients.

While she's never produced anything for television before, Zellweger served as an executive producer on her 2006 film Miss Potter. The TV movie's premiere is set for October, National Breast Cancer Awareness month.