Mekhi Phifer and Jennifer Beals return to 'Lie to Me,' Rumer Willis joins '90210,' Neil Patrick Harris will host another awards show and more of today's top TV headlines.

The Unusuals looks like one of those funny little shows that could either be a complete bust or a major mid-season breakout -- especially given the cast and crew. The ABC ensemble dramedy stars:

1. Amber Tamblyn. I've loved her since she played Emily on General Hospital, and she has that something-different quality that will surely rocket her to super-stardom ... in an indie-film sort of way. She broke into the mainstream consciousness with Joan of Arcadia, the talk-to-God series that ran from 2003 to 2005. I was so disappointed when Tamblyn's I-see-dead-people series Babylon Fields wasn't picked up last year, but The Unusuals sounds even better.

2. Harold Perrineau. We know him as Michael on Lost, and the actor was disappointed that his character wouldn't have a happy ending with son Walt. But he's on to bigger and better things with his role in The Unusuals. It was also announced today that he's joining the cast of (and exec producing) the feature film The Killing Jar, an indie thriller also starring Michael Madsen and Danny Trejo. It was time for Perrineau to leave the island.

Just last week, Harold Perrineau was wondering why his character was killed off on Lost, wishing the producers hadn't blown Michael up with the freighter. He wasn't out of work for long. Harold Perrineau has just been cast on a new ABC comedy/drama called The Unusuals. The pilot, which could be a mid-season replacement on ABC, is an hour set in a New York City police precinct.

Harold will play Detective Leo Banks, an agitated cop who's so afraid of being shot or attacked that he's never without his Kevlar bullet-proof vest. (Does he wear it in the john?) Sounds potentially funny. The writer of The Unusuals is Bones' Noah Hawley and the executive producer is Peter Tolan (Rescue Me, The Larry Sanders Show), so there will be an emphasis on humor. Maybe not full-out Barney Miller, but still funny.

There was more pilot news percolating out of ABC yesterday, including three dramas and a sitcom. On the funny side, writer/producers Jennifer Konner and Alexandra Rushfield are working on Bad Mother's Handbook. It follows the life of a busy, thirtysomething mom dealing with the needs/wants/desires of her teenaged daughter and 48-year old mother. Hmm, sounds like a close knit family! You think they're all under one roof? The sitcom will be a single-camera affair, half-hour laugh fest (or so we hope). I vote for Jamie Lee Curtis as the 48-year old mom. She can still play 48; yes, she can. She looks great on those yogurt commercials!