Jimmy Kimmel is one of the hardest working men in show business, and that's not just some BS title. The guy works overtime on Jimmy Kimmel Live!, no matter how he feels; he even came in the day after a reaction to pain medication swelled his face so badly he couldn't open his eyes.

But even Kimmel can get knocked out by an inflamed appendix. I just got a note from Kimmel's PR rep, Lewis Kay, explaining that Kimmel had to undergo an emergency appendectomy last night, and that the remaining tapings of Jimmy Kimmel Live! this week have been canceled. "He is resting comfortably and is looking forward to getting back to work," says the statement. Knowing Jimmy, he'll try to get back to work on Monday, but I'd imagine he'll be out for at least a couple of weeks.